In Proportion As The Preparation Of The Curare Is Simple, That Of The Poison Of Moyobamba Is A Long And Complicated Process.

With the juice of the bejuco de ambihuasca, which is the principal ingredient, are mixed pimento, tobacco, barbasco (Jacquinia armillaris), sanango (Tabernae montana), and the milk of some other apocyneae.

The fresh juice of the ambihuasca has a deleterious action when in contact with the blood; the juice of the mavacure is a mortal poison only when it is concentrated by fire; and ebullition deprives the juice of the root of Jatropha manihot (the manioc) of all its baneful qualities. In rubbing a long time between my fingers the liana which yields the potent poison of La Peca, when the weather was excessively hot, my hands were benumbed; and a person who was employed with me felt the same effects from this rapid absorption by the uninjured integuments.

I shall not here enter into any detail on the physiological properties of those poisons of the New World which kill with the same promptitude as the strychneae of Asia,* (* The nux vomica, the upas tieute, and the bean of St. Ignatius, Strychnos Ignatia.) but without producing vomiting when they are received into the stomach, and without denoting the approach of death by the violent excitement of the spinal marrow. Scarcely a fowl is eaten on the banks of the Orinoco which has not been killed with a poisoned arrow; and the missionaries allege that the flesh of animals is never so good as when this method is employed. Father Zea, who accompanied us, though ill of a tertian fever, every morning had the live fowls allotted for our food brought to his hammock together with an arrow, and he killed them himself; for he would not confide this operation, to which he attached great importance, to any other person. Large birds, a guan (pava de monte) for instance, or a curassao (alector), when wounded in the thigh, die in two or three minutes; but it is often ten or twelve minutes before life is extinct in a pig or a peccary. M. Bonpland found that the same poison, bought in different villages, varied much. We had procured at the river Amazon some real Ticuna poison which was less potent than any of the varieties of the curare of the Orinoco. Travellers, on arriving in the missions, frequently testify their apprehension on learning that the fowls, monkeys, guanas, and even the fish which they eat, have been killed with poisoned arrows. But these fears are groundless. Majendie has proved by his ingenious experiments on transfusion, that the blood of animals on which the bitter strychnos of India has produced a deleterious effect, has no fatal action on other animals. A dog received a considerable quantity of poisoned blood into his veins without any trace of irritation being perceived in the spinal marrow.

I placed the most active curare in contact with the crural nerves of a frog, without perceiving any sensible change in measuring the degree of irritability of the organs, by means of an arc formed of heterogeneous metals. Galvanic experiments succeeded upon birds, some minutes after I had killed them with a poisoned arrow. These observations are not uninteresting, when we recollect that a solution of the upas-poison poured upon the sciatic nerve, or insinuated into the texture of the nerve, produces also a sensible effect on the irritability of the organs by immediate contact with the medullary substance. The danger of the curare, as of most of the other strychneae (for we continue to believe that the mavacure belongs to a neighbouring family), results only from the action of the poison on the vascular system. At Maypures, a zambo descended from an Indian and a negro, prepared for M. Bonpland some of those poisoned arrows, that are shot from blowing-tubes to kill small monkeys or birds. He was a man of remarkable muscular strength. Having had the imprudence to rub the curare between his fingers after being slightly wounded, he fell on the ground seized with a vertigo, that lasted nearly half an hour. Happily the poison was of that diluted kind which is used for very small animals, that is, for those which it is believed can be recalled to life by putting muriate of soda into the wound. During our passage in returning from Esmeralda to Atures, I myself narrowly escaped an imminent danger. The curare, having imbibed the humidity of the air, had become fluid, and was spilt from an imperfectly closed jar upon our linen. The person who washed the linen had neglected to examine the inside of a stocking, which was filled with curare; and it was only on touching this glutinous matter with my hand, that I was warned not to draw on the poisoned stocking. The danger was so much the greater, as my feet at that time were bleeding from the wounds made by chegoes (Pulex penetrans), which had not been well extirpated. This circumstance may warn travellers of the caution requisite in the conveyance of poisons.

An interesting chemical and physiological investigation remains to be accomplished in Europe on the poisons of the New World, when, by more frequent communications, the curare de bejuco, the curare de raiz, and the various poisons of the Amazon, Guallaga, and Brazil, can be procured, without being confounded together, from the places where they are prepared. Since the discovery of prussic acid,* (* First obtained by Scheele in the year 1782. Gay-Lussac (to whom we are indebted for the complete analysis of this acid) observes that it can never become very dangerous to society, because its peculiar smell (that of bitter almonds) betrays its presence, and the facility with which it is decomposed makes it difficult to preserve.) and many other new substances eminently deleterious, the introduction of poisons prepared by savage nations is less feared in Europe; we cannot however appeal too strongly to the vigilance of those who keep such noxious substances in the midst of populous cities, the centres of civilization, misery, and depravity.

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